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Miami Headache Blog

Antidepressants and Headaches

Gabriel Santos - Wednesday, September 10, 2014

Payman Sadeghi, MD

Antidepressants Could be Used to Treat Headaches

Studies have suggested that certain antidepressants could be used to reduce the severity and frequency of some forms of headache, including chronic migraine.

Tricyclic antidepressants such as amitriptyline are very effective as they have an effect on the amount of serotonin and other chemicals present in the brain. Other antidepressants such as SSRIs (selective serotonin reuptake inhibitors) have not been proven to be effective for the prevention or reduction of migraine symptoms. However, other drugs such as venlafaxine (Effexor) and SNRI have shown signs of success.

    These studies are ongoing and are not conclusive yet. Research is currently being carried out between patients already receiving antidepressants for depression and those who have been given medication to specifically treat their headaches. We will be sure to bring you the latest research results once they are released.

Good News and Bad News for Headache Sufferers

Unfortunately, it is not all good news for headache patients as antidepressants can cause other side effects that may be unwanted and which may turn out to be worse than the headaches.

Side effects vary between different medications, but can include fatigue, weight gain, dry mouth and constipation. These side effects can make it very difficult for a patient to see this treatment through.

Should You Consider Taking A Migraine Prevention Drug?

Before you start to take a drug for preventing the onset or severity of your headaches, you should know that success is not guaranteed. In fact, only 10% of people who take prevention medicines are completely free from headaches.  

At Miami Headache Institute, we have proved time and time again that it is possible to free yourself from headaches and migraine and we welcome you to our clinic for a thorough diagnosis.

Why Seek An Expert Headache Diagnosis?

Headaches can be debilitating, frustrating and can take over your life. Don’t suffer in silence—we can help you to find a long term cure.

At the Miami Headache Institute, we specialize in treating many different types of headaches and stay on top of the latest diagnosis and treatment techniques. Speak to our team today to find out more about the use of prescription drugs and the various alternative therapies that are available.

Speak to the team today at Miami Headache Institute and get personalized advice for your headaches and migraine attacks. Call us at 305.440.5969 or use our contact form to book a consultation.

 Dr. Payman Sadeghi is the founder of the Miami Headache and Neurological Institute. He studied medicine at Nordestana University and finished his Internal Medicine internship and Neurology residency at the University of Texas.  Dr. Sadeghi has completed an electromyography super fellowship as well as many epilepsy and neuroimaging fellowships. At his residency in Neurology at the University of Texas Medical Branch Dr. Sadeghi gained extensive experience diagnosing and treating headache and migraine patients. That residency, along with Dr. Sadeghi's medical curiosity and his varied clinical experience, has made him a specialist in headaches and their treatment.

Dr. Sadeghi was also a clinical assistant professor during his time at the University of Texas. He is a member of the American Headache Society, the National Headache Foundation and the American Academy of Neurology. Dr. Sadeghi is fluent in English, Spanish, French and Persian.


Don’t let the stresses of life get in the way of what’s truly important

Our migraine & headache experts can help you. The Miami Headache Institute uses the latest technology and treatments to ensure the most effective results. Contact us today.




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